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Autoclaves are used in education, research, biomedical research, pharmaceutical research and industrial settings to sterilize lab instruments and glassware, process waste loads prior to disposal, prepare culture media and liquid media, and artificially age materials for testing. Although autoclaves produced for use in medicine may be used in ...
Aseptic processing was derived from Olin Ball's heat-cool-fill (HCF) machine that was developed in 1927. [5] While HCF was successful in improving the sensory quality of the processed chocolate milk as compared to canned product, the use of the equipment was hindered by its cost, maintenance, and inflexibility to process various container sizes, rendering the machine a failure.
The quantitatively described steam quality (steam dryness) is the proportion of saturated steam in a saturated water/steam mixture. In other words, a steam quality of 0 indicates 100% liquid, while a steam quality of 1 (or 100%) indicates 100% steam. The quality of steam on which steam whistles are blown is variable and may affect frequency.
A waste autoclave is a form of solid waste treatment that uses heat, steam and pressure of an industrial autoclave in the processing of waste. Waste autoclaves process waste either in batches or in continuous-flow processes. In batch processes, saturated steam is pumped into the autoclave at temperatures around 160 °C, or 320 °F. [1]
This method is a faster process than dry heat sterilization. Steam sterilization is performed using an autoclave, sometimes called a converter or steam sterilizer. The object or liquid is placed in the autoclave chamber, which is then sealed and heated using pressurized steam to a temperature set point for a defined period of time.
Process performance qualification protocol is a component of process validation: process qualification.This step is vital in maintaining ongoing production quality by recording and having available for review essential conditions, controls, testing, and expected manufacturing outcome of a production process.
The purpose of process validation is to ensure varied inputs lead to consistent and high quality outputs. Process validation is an ongoing process that must be frequently adapted as manufacturing feedback is gathered. End-to-end validation of production processes is essential in determining product quality because quality cannot always be ...
"Process validation is defined as the collection and evaluation of data, from the process design stage through commercial production, which establishes scientific evidence that a process is capable of consistently delivering quality product. Process validation involves a series of activities taking place over the lifecycle of the product and ...