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  2. Interferon beta-1b - Wikipedia

    en.wikipedia.org/wiki/Interferon_beta-1b

    Interferon beta-1b is a cytokine in the interferon family used to treat the relapsing-remitting and secondary-progressive forms of multiple sclerosis (MS). It is approved for use after the first MS event. Closely related is interferon beta 1a, also indicated for MS, with a very similar drug profile.

  3. Interferon beta-1a - Wikipedia

    en.wikipedia.org/wiki/Interferon_beta-1a

    Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). [5] It is produced by mammalian cells, while interferon beta-1b is produced in modified E. coli. [6] Some research indicates that interferon injections may result in an 18–38% reduction in the rate of MS relapses. [7]

  4. Management of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Management_of_multiple...

    In 1993, interferon beta-1b was the first drug to ever be approved for MS, being soon followed by interferon beta-1a and glatiramer acetate. [ 25 ] Interferon beta-1a is injected either weekly ( intramuscular injection ) or three times a week ( subcutaneous injection ) depending on commercial formulations, [ 26 ] [ 27 ] while interferon beta-1b ...

  5. Peginterferon beta-1a - Wikipedia

    en.wikipedia.org/wiki/Peginterferon_Beta-1a

    Peginterferon beta-1a, sold under the brand name Plegridy, is medication used to treat multiple sclerosis. [4] [5]The most common side effects include headache, muscle pain, joint pain, influenza (flu)-like symptoms, pyrexia (fever), chills, asthenia (weakness), and erythema (reddening of the skin), pain or pruritus (itching) at the injection site.

  6. Interferon - Wikipedia

    en.wikipedia.org/wiki/Interferon

    Interferon beta-1a and interferon beta-1b are used to treat and control multiple sclerosis, an autoimmune disorder. This treatment may help in reducing attacks in relapsing-remitting multiple sclerosis [43] and slowing disease progression and activity in secondary progressive multiple sclerosis. [44]

  7. Multiple sclerosis drug pipeline - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis_drug...

    Cyclophosphamide and Beta-Interferon has been tried on IFNbeta-unresponsive patients with success, but it is still under study. [137] Avonex and inosine: Avonex (interferon beta-1a) was combined with inosine. Available data suggests that this combination is safe and well tolerated, though with no improvements respect interferon beta alone.

  8. Multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis

    Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease, MS disrupts the nervous system's ability to transmit signals, resulting in a range of signs and symptoms, including physical, mental, and sometimes psychiatric problems.

  9. IFNB1 - Wikipedia

    en.wikipedia.org/wiki/IFNB1

    Interferon beta is a protein that in humans is encoded by the IFNB1 gene. [5] The natural and recombinant protein forms have antiviral, antibacterial, and anticancer properties. Interferon beta 1a (tradenames: Avonex and Rebif) and Interferon beta 1b (tradenames: Betaseron/Betaferon) are used as drugs.

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