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The length of the human colon is, on average 160.5 cm (measured from the bottom of the cecum to the colorectal junction) with a range of 80 cm to 313 cm. [11] The average inner circumference of the colon is 6.2 cm. [10] Thus, the inner surface epithelial area of the human colon has an area, on average, of about 995 cm 2, which includes ...
(c) posterior ileocolic, mostly placed in the angle between the ileum and the colon, but partly lying behind the cecum at its junction with the ascending colon; (d) a single gland, between the layers of the mesenteriole of the appendix; (e) right colic, along the medial side of the ascending colon.
Subsets of sensory intestinal epithelial cells synapse with nerves, [9] and are known as neuropod cells. [10] Paneth cells produce antimicrobial peptides such as human alpha-defensin. [11] [12] Microfold cells (commonly referred to as M cells) sample antigens from the lumen and deliver them to the lymphoid tissue associated with the mucosa (MALT).
The most common form of colon cancer is adenocarcinoma, constituting between 95% [2] and 98% [3] of all cases of colorectal cancer. Other, rarer types include lymphoma, adenosquamous and squamous cell carcinoma. Some subtypes have been found to be more aggressive. [4]
The ileum (/ ˈ ɪ l i əm /) is the final section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds.In fish, the divisions of the small intestine are not as clear and the terms posterior intestine or distal intestine may be used instead of ileum. [2]
The gut-associated lymphoid tissue lies throughout the intestine, covering an area of approximately 260–300 m 2. [5] In order to increase the surface area for absorption, the intestinal mucosa is made up of finger-like projections (), covered by a monolayer of epithelial cells, which separates the GALT from the lumen intestine and its contents.
The field defect adjacent to a colon cancer consists of the inner surface of the colon (the epithelium) that has about 1 million crypts (indentations in the surface of the epithelium). [21] Each crypt has about 5,000 cells in the shape of a test-tube and all 5,000 cells of the crypt are generated from the few stem cells at the base of the crypt.
Squamous cell cancer, upper oesophagus. Gastrointestinal cancer refers to malignant conditions of the gastrointestinal tract (GI tract) and accessory organs of digestion, including the esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum and anus. The symptoms relate to the organ affected and can include ...
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