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E-liquid exposure whether intentional or unintentional from ingestion, eye contact, or skin contact can cause adverse effects such as seizures and anoxic brain trauma. [16] The nicotine in e-liquids readily absorbs into the bloodstream when a person uses an e-cigarette. [ 30 ]
As of 2014, calls to US poison control centers involved inhalations, eye exposures, skin exposures, and ingestion, in both adults and children. [117] A 2016 study reported minor, moderate, and serious adverse effects. [118] Minor effects correlated with e-liquid poisoning were tachycardia, tremor, chest pain and hypertension.
“Menthol-flavored e-cigarettes are highly attractive to kids. And this is a one-two combination of a flavor plus such high levels of nicotine, and that’s a recipe for disaster,” Sward said.
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
The FDA said it authorized four menthol e-cigarettes from NJOY, the vaping brand recently acquired by tobacco giant Altria, which also makes Marlboro cigarettes.
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Smoking is associated with a decreased risk of Parkinson's disease; however, it is unknown whether this is due to people with healthier brain dopaminergic reward centers (the area of the brain affected by Parkinson's) being more likely to enjoy smoking and thus pick up the habit, nicotine directly acting as a neuroprotective agent, or other ...
The long-term effects of e-cigarette use are unknown. [66] [76] [77] The risk from serious adverse events was reported in 2016 to be low. [78] Less serious adverse effects include abdominal pain, headache, blurry vision, [79] throat and mouth irritation, vomiting, nausea, and coughing. [80] Nicotine itself is associated with some health harms. [81]