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Malathion is an acetylcholinesterase inhibitor, a diverse family of chemicals.Upon uptake into the target organism, it binds irreversibly to the serine residue in the active catalytic site of the cholinesterase enzyme.
Extrapyramidal symptoms (EPS) are symptoms that are archetypically associated with the extrapyramidal system of the brain's cerebral cortex. When such symptoms are caused by medications or other drugs, they are also known as extrapyramidal side effects (EPSE). The symptoms can be acute (short-term) or chronic (long-term).
Standard treatment for nerve agent poisoning is a combination of an anticholinergic to manage the symptoms, and an oxime as an antidote. [12] Anticholinergics treat the symptoms by reducing the effects of acetylcholine, while oximes displaces phosphate molecules from the active site of the cholinesterase enzymes, allowing the breakdown of ...
These antidepressant effects are thought to be related to the drug's action on the glutamate receptor system and the relative spike in glutamate levels, as well as its interaction with mTOR, which is an enzymatic protein involved in catabolic processes in the human body.
Affect, in psychology, is the underlying experience of feeling, emotion, attachment, or mood. [1] It encompasses a wide range of emotional states and can be positive ...
Abnormal psychology is the study of abnormal behavior in order to describe, predict, explain, and change abnormal patterns of functioning. Abnormal psychology studies the nature of psychopathology and its causes, and this knowledge is applied in clinical psychology to treat patients with psychological disorders.
One such region is the nucleus accumbens—a key part of the brain’s reward system that’s fueled by dopamine, a chemical that Wise fondly refers to as “the slutty neurotransmitter” because ...
Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD). [1] Further, nutritional deficiencies in magnesium, [2] vitamin D, [3] and tryptophan have been linked with depression; these deficiencies may be caused by the individual's environment, but they have a biological impact.