Search results
Results from the WOW.Com Content Network
Primary age-related tauopathy (PART) is a neuropathological designation introduced in 2014 to describe the neurofibrillary tangles (NFT) that are commonly observed in the brains of normally aged and cognitively impaired individuals that can occur independently of the amyloid plaques of Alzheimer's disease (AD).
Histopathologic images of Alzheimer's disease, in the CA3 area of the hippocampus, showing an amyloid plaque (top right), neurofibrillary tangles (bottom left), and granulovacuolar degeneration bodies (bottom center) Alzheimer's disease is characterised by loss of neurons and synapses in the cerebral cortex and certain
The hippocampal neuronal cell loss and gliosis are disproportionate to the Alzheimer's disease "neuropathological change in the same section." [13] One sided hippocampal sclerosis has a 40-50% prevalence even when the TDP-43 inclusions involve both sides of the brain.
Alzheimer's disease (AD) is a chronic neurodegenerative disease that results in the loss of neurons and synapses in the cerebral cortex and certain subcortical structures, resulting in gross atrophy of the temporal lobe, parietal lobe, and parts of the frontal cortex and cingulate gyrus. [14]
In Alzheimer's disease (and other forms of dementia), the hippocampus is one of the first regions of the brain to suffer damage; [137] short-term memory loss and disorientation are included among the early symptoms.
This is an accepted version of this page This is the latest accepted revision, reviewed on 11 February 2025. Long-term brain disorders causing impaired memory, thinking and behavior This article is about the cognitive disorder. For other uses, see Dementia (disambiguation). "Senile" and "Demented" redirect here. For other uses, see Senile (disambiguation) and Demented (disambiguation). Medical ...
Posterior cortical atrophy (PCA), also called Benson's syndrome, is a rare form of dementia which is considered a visual variant or an atypical variant of Alzheimer's disease (AD). [ 1 ] [ 2 ] [ 3 ] The disease causes atrophy of the posterior part of the cerebral cortex , resulting in the progressive disruption of complex visual processing . [ 4 ]
It is an uncommon form of Alzheimer's, accounting for only 5–10% of all Alzheimer's cases. About 60% have a positive family history of Alzheimer's and 13% of them are inherited in an autosomal dominant manner. Most cases of early-onset Alzheimer's share the same traits as the "late-onset" form and are not caused by known genetic mutations.