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Chylomicron structure ApoA, ApoB, ApoC, ApoE (apolipoproteins); T (triacylglycerol); C (cholesterol); green (phospholipids). Chylomicrons transport lipids absorbed from the intestine to adipose, cardiac, and skeletal muscle tissue, where their triglyceride components are hydrolyzed by the activity of the lipoprotein lipase, allowing the released free fatty acids to be absorbed by the tissues.
Remnant cholesterol is the cholesterol content of triglyceride-rich lipoproteins, which consist of very low-density lipoproteins and intermediate-density lipoproteins with chylomicron remnants. [2] [5] Remnant cholesterol is primarily chylomicron and VLDL, and each remnant particle contains about 40 times more cholesterol than LDL. [6]
Even people with very low LDL levels achieved by statin treatment are exposed to increased risk if their HDL levels are not high enough. [19] [non-primary source needed] Very high HDL-C levels (≥80 mg/dL in men, ≥100 mg/dL in women) appears to be detrimental to cardiovascular outcomes.
Hyperlipidemia is abnormally high levels of any or all lipids (e.g. fats, triglycerides, cholesterol, phospholipids) or lipoproteins in the blood. [2] The term hyperlipidemia refers to the laboratory finding itself and is also used as an umbrella term covering any of various acquired or genetic disorders that result in that finding. [3]
Chylomicron retention disease is a disorder of fat absorption. [1] It is associated with SAR1B . [ 2 ] Mutations in SAR1B prevent the release of chylomicrons in the circulation which leads to nutritional and developmental problems. [ 3 ]
Over 45 for men and over 55 for women. Family history. Having a family history of early heart disease. Sex. People born male are at increased risk. Congenital defects. Having problems with your ...
The Mayo Clinic diet, a program that adheres to this notion, was developed by medical professionals based on scientific research, so you can trust that this program is based on science, and not ...
Structure of a chylomicron (the largest lipoprotein). ApoA , ApoB , ApoC , ApoE are apolipoproteins ; green particles are phospholipids ; T is triglyceride ; C is cholesterol ester . A lipoprotein is a biochemical assembly whose primary function is to transport hydrophobic lipid (also known as fat ) molecules in water, as in blood plasma or ...