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Some drugs, such as medroxyprogesterone acetate, cyproterone acetate and LHRH agonists can decrease serum testosterone and estradiol in the body, thus impairing the metabolism of glucose and lipid. These drugs can also cause depression, hot flashes , infertility and anemia , aside from cardiovascular diseases and osteoporosis.
Medroxyprogesterone acetate (MPA), also known as depot medroxyprogesterone acetate (DMPA) in injectable form and sold under the brand name Depo-Provera among others, is a hormonal medication of the progestin type. [10] [4] It is used as a method of birth control and as a part of menopausal hormone therapy.
Medroxyprogesterone, also known as 6α-methyl-17α-hydroxyprogesterone or as 6α-methyl-17α-hydroxypregn-4-en-3,20-dione, is a synthetic pregnane steroid and a derivative of progesterone. [ 2 ] [ 3 ] It is specifically a derivative of 17α-hydroxyprogesterone with a methyl group at the C6α position.
Nearly 2 in 3 people who sought to lose weight quit popular weight loss and diabetes drugs such as Ozempic or Victoza within one year, according to a new study. About 65% of those without diabetes ...
While these GLP-1 drugs are not recommended for short-term use, people stop taking them for a variety of reasons, including reaching their weight loss goals, severity of side effects, and cost.
These medications are typically administered via injections or implants. Another type of puberty blocker includes progestins, such as medroxyprogesterone acetate, which can be taken orally or by injection and work by reducing the body's production of sex hormones.
Medications may be stopped in the context of end-of-life care, such as medications that may affect risk factors for future disease. Medications that may be stopped as part of discussions about end-of-life care include antihypertensives , medications for diabetes , and drugs for high cholesterol .
Antiandrogens such as cyproterone acetate and medroxyprogesterone acetate, or the LHRH agonist leuprolide, are sometimes prescribed to convicted male sex offenders who are released on parole in an effort to stop them reoffending, in a treatment sometimes referred to as chemical castration, however the high doses required often cause a range of ...