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The term Cox regression model (omitting proportional hazards) is sometimes used to describe the extension of the Cox model to include time-dependent factors. However, this usage is potentially ambiguous since the Cox proportional hazards model can itself be described as a regression model.
The Cox regression results are interpreted as follows. Sex is encoded as a numeric vector (1: female, 2: male). The R summary for the Cox model gives the hazard ratio (HR) for the second group relative to the first group, that is, male versus female. coef = 0.662 is the estimated logarithm of the hazard ratio for males versus females.
Cox processes are used to generate simulations of spike trains (the sequence of action potentials generated by a neuron), [2] and also in financial mathematics where they produce a "useful framework for modeling prices of financial instruments in which credit risk is a significant factor."
For two groups that differ only in treatment condition, the ratio of the hazard functions is given by , where is the estimate of treatment effect derived from the regression model. This hazard ratio, that is, the ratio between the predicted hazard for a member of one group and that for a member of the other group, is given by holding everything ...
A well-known example of a semiparametric model is the Cox proportional hazards model. [3] If we are interested in studying the time to an event such as death due to cancer or failure of a light bulb, the Cox model specifies the following distribution function for :
R 2 L is given by Cohen: [1] =. This is the most analogous index to the squared multiple correlations in linear regression. [3] It represents the proportional reduction in the deviance wherein the deviance is treated as a measure of variation analogous but not identical to the variance in linear regression analysis. [3]
The logrank test statistic compares estimates of the hazard functions of the two groups at each observed event time. It is constructed by computing the observed and expected number of events in one of the groups at each observed event time and then adding these to obtain an overall summary across all-time points where there is an event.
Conditional logistic regression is available in R as the function clogit in the survival package. It is in the survival package because the log likelihood of a conditional logistic model is the same as the log likelihood of a Cox model with a particular data structure. [3]