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Extracellular substances, such as free mucin, colloid, and ground substance, are also easily stained, and appear metachromatic. Major applications include blood smears , bone marrow aspirates, semen analysis and cytology of various body fluids including urine and cerebrospinal fluid .
Modern complete blood count analyzers can provide an automated white blood cell differential, but they have a limited ability to differentiate immature and abnormal cells, so manual examination of the blood smear is frequently indicated. [5] [6] Blood smear examination is the preferred diagnostic method for certain parasitic infections, such as ...
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Field stain is a histological method for staining of blood smears. It is used for staining thick blood films in order to discover malarial parasites. Field's stain is a version of a Romanowsky stain , used for rapid processing of the specimens.
Plasmodium ovale microgametocyte in Giemsa-stained thin blood film, with annotated Schüffner's dots and hemozoin pigment Trophozoites of P. ovale in thin blood smears. Schüffner's dots can be seen. Schüffner's dots can be seen.
Supravital stain of a smear of human blood from a patient with hemolytic anemia. The reticulocytes are the cells with the dark blue dots and curved linear structures (reticulum) in the cytoplasm. Supravital staining is a method of staining used in microscopy to examine living cells that have been removed from an organism.
Wright's stain is a hematologic stain that facilitates the differentiation of blood cell types. It is classically a mixture of eosin (red) and methylene blue dyes. It is used primarily to stain peripheral blood smears, urine samples, and bone marrow aspirates, which are examined under a light microscope.
Histology image: 01807loa – Histology Learning System at Boston University - "Bone Marrow and Hemopoiesis: bone marrow smear, neutrophil series" Histology at KUMC blood-blood11; Histology image: 75_07 at the University of Oklahoma Health Sciences Center; Histology at okstate.edu; Slide at hematologyatlas.com - "Neutrophil band" visible in ...