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“At high doses, kratom is like an opioid — people go through withdrawal,” she said. ... It has stimulant or sedative effects, depending on the dose. Some people use it to treat anxiety and ...
Mitragyna speciosa is a tropical evergreen tree of the Rubiaceae family (coffee family) native to Southeast Asia. [3] It is indigenous to Cambodia, Thailand, Indonesia, Malaysia, Myanmar, and Papua New Guinea, [4] where its leaves, known as kratom, have been used in herbal medicine since at least the 19th century. [5]
Kratom has been used for hundreds of years in Southeast Asia for issues like fatigue. But it's banned in at least 6 states. Kratom is an herbal supplement with stimulant-like effects.
7-Hydroxymitragynine (7-OH) is a terpenoid indole alkaloid from the plant Mitragyna speciosa, commonly known as kratom. [2] It was first described in 1994 [3] and is a human metabolite metabolized from mitragynine present in the Mitragyna speciosa. 7-OH binds to opioid receptors like mitragynine, but research suggests that 7-OH binds with greater efficacy.
Mitragynine is an indole-based alkaloid and is one of the main psychoactive constituents in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. [4] It is an opioid that is typically consumed as a part of kratom for its pain-relieving and euphoric effects.
At low doses, kratom causes a stimulant effect similar to coffee. At higher ones, it can produce an opioid-like, euphoric state that the federal Drug Enforcement Administration says has led to a ...
About 1.7 million Americans ages 12 and older were estimated to be kratom users in 2021. In smaller doses, kratom can produce stimulant effects, according to the Centers for Disease Control and ...
Speciociliatine is a major alkaloid of the plant Mitragyna speciosa, commonly known as kratom. It is a stereoisomer of Mitragynine and constitutes 0.00156 - 2.9% of the dried leaf material. [ 2 ] [ 3 ]