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Drugs which cause disulfiram-like reactions upon ingestion of alcohol as an unintended effect include: [6] [1] [7] Abacavir Cephalosporins , but only these with a methylthiotetrazole side chain or a methylthiodioxotriazine ring; thought to be due to common N -methylthiotetrazole metabolite , which is similar in structure to disulfiram. [ 8 ]
Disulfiram-alcohol reaction (DAR) is the effect of the interaction in the human body of alcohol drunk with disulfiram or some types of mushrooms. [ 1 ] [ 2 ] The DAR is key to disulfiram therapy that is widely used for alcohol-aversive treatment and management of other addictions (e.g. cocaine [ 3 ] [ 4 ] use).
Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [ 2 ] [ 3 ] [ 4 ] Salts of this anion, especially docusate sodium , are widely used in medicine as an emollient laxative and as stool softeners , by mouth or rectally. [ 1 ]
Bottom line: Most drugs carry a risk, but if you've been prescribed an oral or injected fluoroquinolone and you're concerned about side effects, be sure to talk to your doctor about switching.
A new federal report shows that one drink per day could raise the risk of liver damage and several cancers. The report follows a recommendation by the U.S. Surgeon General on safe alcohol ...
Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [3]), causing many of the effects of a hangover to be felt immediately following alcohol consumption.
Interactions between alcohol and certain antibiotics may occur and may cause side effects and decreased effectiveness of antibiotic therapy. [60] [61] While moderate alcohol consumption is unlikely to interfere with many common antibiotics, there are specific types of antibiotics with which alcohol consumption may cause serious side effects. [62]
Alcohol-related deaths have climbed nationally in the past few years: The U.S. saw a 25% spike in deaths during the first year of the pandemic, a trend that particularly affected middle-aged adults.