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  2. Loading dose - Wikipedia

    en.wikipedia.org/wiki/Loading_dose

    In pharmacokinetics, a loading dose is an initial higher dose of a drug that may be given at the beginning of a course of treatment before dropping down to a lower maintenance dose.

  3. Volume of distribution - Wikipedia

    en.wikipedia.org/wiki/Volume_of_distribution

    In pharmacology, the volume of distribution (V D, also known as apparent volume of distribution, literally, volume of dilution [1]) is the theoretical volume that would be necessary to contain the total amount of an administered drug at the same concentration that it is observed in the blood plasma. [2]

  4. Maintenance dose - Wikipedia

    en.wikipedia.org/wiki/Maintenance_dose

    In pharmacokinetics, a maintenance dose is the maintenance rate [mg/h] of drug administration equal to the rate of elimination at steady state. This is not to be confused with dose regimen, which is a type of drug therapy in which the dose [mg] of a drug is given at a regular dosing interval on a repetitive basis.

  5. Antiarrhythmic agent - Wikipedia

    en.wikipedia.org/wiki/Antiarrhythmic_agent

    (The re-entrant rhythm is less likely to interact with tissue that has become refractory). The class III agents exhibit reverse-use dependence (their potency increases with slower heart rates, and therefore improves maintenance of sinus rhythm). Inhibiting potassium channels results in slowed atrial-ventricular myocyte repolarization.

  6. Amiodarone - Wikipedia

    en.wikipedia.org/wiki/Amiodarone

    Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of cardiac dysrhythmias. [4] This includes ventricular tachycardia, ventricular fibrillation, and wide complex tachycardia, atrial fibrillation, and paroxysmal supraventricular tachycardia. [4]

  7. Gang-tied illegal immigrant ‘giggled’ as he confessed to ...

    www.aol.com/gang-tied-illegal-immigrant-giggled...

    A Honduras gang member who was illegally in the US “giggled” as he admitted kidnapping a young Texas woman at gunpoint and threatening to pimp her out and sell her organs, according to cops.

  8. Rate of infusion - Wikipedia

    en.wikipedia.org/wiki/Rate_of_infusion

    In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective. Abbreviations include K in, [1] K 0, [2] or R 0.

  9. Families fight outside Vegas court after murder hearing for ...

    www.aol.com/families-fight-outside-vegas-court...

    A Las Vegas courthouse descended into chaos when two families fought following a court hearing for a man accused of gunning down his girlfriend before going to sleep and calling police about the ...