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This is the list of Schedule I controlled substances in the United States as defined by the Controlled Substances Act. [1]
Factor VIII, an essential blood coagulation protein, [12] is used as a medication to treat and prevent bleeding in people with hemophilia A and other causes of low factor VIII. [ 13 ] [ 14 ] Certain preparations may also be used in those with von Willebrand's disease . [ 14 ]
Efanesoctocog alfa is a recombinant DNA-derived, Factor VIII concentrate indicated for use in adults and children with hemophilia A (congenital factor VIII deficiency) for routine prophylaxis to reduce the frequency of bleeding episodes; on-demand treatment & control of bleeding episodes; and perioperative management of bleeding. [1] [4]
1 in 7,500 males (haemophilia A), 1 in 40,000 males (haemophilia B) [2] [5] Haemophilia ( British English ), or hemophilia ( American English ) [ 6 ] (from Ancient Greek αἷμα ( haîma ) 'blood' and φιλία ( philía ) 'love of'), [ 7 ] is a mostly inherited genetic disorder that impairs the body's ability to make blood clots , a process ...
Acquired haemophilia A (AHA) is a rare but potentially life-threatening bleeding disorder characterized by autoantibodies directed against coagulation factor VIII.These autoantibodies constitute the most common spontaneous inhibitor to any coagulation factor and may induce spontaneous bleeding in patients with no previous history of a bleeding disorder.
Treatment of adults with moderate to severe hemophilia B (congenital factor IX deficiency) who are receiving routine prophylaxis and without pre-existing neutralizing antibodies to adeno-associated virus serotype Rh74var (AAVRh74var) capsid detected by an FDA-approved test.
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