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Oleoylethanolamide (OEA) is an endogenous peroxisome proliferator-activated receptor alpha (PPAR-α) agonist.It is a naturally occurring ethanolamide lipid that regulates feeding and body weight in vertebrates ranging from mice to pythons.
Hydroxyethyl starch (HES/HAES), sold under the brand name Voluven among others, is a nonionic starch derivative, used as a volume expander in intravenous therapy.The use of HES on critically ill patients is associated with an increased risk of death and kidney problems.
Topical steroids are the topical forms of corticosteroids.Topical steroids are the most commonly prescribed topical medications for the treatment of rash and eczema.Topical steroids have anti-inflammatory properties and are classified based on their skin vasoconstrictive abilities. [1]
Micrograph of fatty liver, as may be seen due to long-term prednisone use. Trichrome stain.. Short-term side effects, as with all glucocorticoids, include high blood glucose levels (especially in patients with diabetes mellitus or on other medications that increase blood glucose, such as tacrolimus) and mineralocorticoid effects such as fluid retention. [24]
Oleylamine reacts with carboxylic acid to form its carboxylate salt through an exothermic reaction. [8] [9] Its carboxylate salt can further condensate into amides through the loss of one water molecule. In the presence of acetic acid, oleylamin forms with DNA insoluble complexes with the radii of the particles equal 60–65 nm. [10]
[8] [9] Some in-vitro studies show that cis-oleamide is an agonist for the cannabinoid receptor CB-1 with an affinity around 8 micromolar. [10] However, given oleamide's relatively low affinity for CB-1 and uncertainty about the concentration and biological role of oleamide in-vivo, it has been argued that it is premature to classify oleamide ...
Some common side effects include burning and stinging sensations. [10] [11] [21] [25] Colour change of the skin, bump formation on the skin and additional hair growth could also occur. [11] [19] Consult a doctor if these side effects persist or become worse. [11] [19] Some severe side effects are severe rash, swelling of the skin, and skin ...
The analgesic and antihyperalgesic effects of PEA in two models of acute and persistent pain seemed to be explained at least partly via the de novo neurosteroid synthesis. [ 24 ] [ 25 ] In chronic granulomatous pain and inflammation model, PEA could prevent nerve formation and sprouting, mechanical allodynia, and PEA inhibited dorsal root ...
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