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LEEP cone biopsy displaying normal cervical epithelium (far left) progressing to borderline koilocytosis, to LSIL, and to HSIL (far right). A squamous intraepithelial lesion (SIL) is an abnormal growth of epithelial cells on the surface of the cervix, commonly called squamous cells.
When examining cytologic specimens, a diagnosis of ASC-US is given if squamous cells are suspicious for low-grade squamous intraepithelial lesion (LSIL) but do not fulfill the criteria. This may be due to limitations in the quality of the specimen, or because the abnormalities in the cells are milder than that seen in LSIL. [ 6 ]
Of all women with HSIL results, 2% [8] or less [9] have invasive cervical cancer at that time, however about 20% would progress to having invasive cervical cancer without treatment. [ 10 ] [ needs update ] To combat this progression, HSIL is usually followed by an immediate colposcopy with biopsy to sample or remove the dysplastic tissue.
Although more than 20% of cervical cancer cases are found in women over 65, these cancers “rarely occur” in those who have been getting regular cervical cancer screenings before they were 65 ...
Over a recent two-decade span, mounting research shows the United States has made almost no progress in eliminating racial disparities in key health indicators, even as political and public health ...
Some tests which detect cancer could be called "screening for epithelial dysplasia". The principle behind these tests is that physicians expect dysplasia to occur at the same rate in a typical individual as it would in many other people.
Many women with HPV infection never develop CIN or cervical cancer. Typically, HPV resolves on its own. [4] However, those with an HPV infection that lasts more than one or two years have a higher risk of developing a higher grade of CIN. [5] Like other intraepithelial neoplasias, CIN is not cancer and is usually curable. [3]
Anal dysplasia is a pre-cancerous condition which occurs when the lining of the anal canal undergoes abnormal changes. It can be classified as low grade squamous intraepithelial lesions (LSIL) and high-grade squamous intraepithelial lesions (HSIL). [1]