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  2. This Christmas, ask for genetic testing. It could save ... - AOL

    www.aol.com/christmas-ask-genetic-testing-could...

    Doctors discovered a lump during her sister's mammogram back in 2008 that came back positive for breast cancer. Genetic testing revealed both had the BRCA gene – one that puts someone at higher ...

  3. MammaPrint - Wikipedia

    en.wikipedia.org/wiki/MammaPrint

    MammaPrint is a prognostic and predictive diagnostic test for early stage breast cancer patients that assess the risk that a tumor will metastasize to other parts of the body. [1] It gives a binary result, high-risk or low-risk classification , and helps physicians determine whether or not a patient will benefit from chemotherapy .

  4. Guidelines say more women may need breast cancer gene test - AOL

    www.aol.com/news/2019-08-26-guidelines-say-more...

    Most cancer isn't caused by BRCA mutations — they account for 5 percent to 10 percent of breast cancers and 15 percent of ovarian cancers — so the gene tests aren't for everyone. But mutations ...

  5. Hereditary lobular breast cancer - Wikipedia

    en.wikipedia.org/wiki/Hereditary_lobular_breast...

    Clinical criteria for genetic testing were suggested as following: (a) bilateral lobular breast cancer with or without family history of breast cancer, with age at onset <50 years; and (b) unilateral lobular breast cancer with family history of breast cancer, with age at onset <45 years. In this context, it has been estimated that the frequency ...

  6. Genetic testing - Wikipedia

    en.wikipedia.org/wiki/Genetic_testing

    Genetic testing is often done as part of a genetic consultation and as of mid-2008 there were more than 1,200 clinically applicable genetic tests available. [23] Once a person decides to proceed with genetic testing, a medical geneticist, genetic counselor, primary care doctor, or specialist can order the test after obtaining informed consent .

  7. 23andMe and breast cancer gene testing: What you should know

    www.aol.com/lifestyle/23andme-breast-cancer-gene...

    While the BRCA gene, known as the "breast cancer gene," is only found in 1 in 400 people and accounts for between 5 to 10 percent of breast cancer cases and 15 percent of ovarian cancer cases, it ...

  8. Breast cancer classification - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_classification

    The commercial test is marketed for use in breast cancer irrespective of estrogen receptor (ER) status. [72] The test is run on formalin fixed, paraffin-embedded tissue. MammaPrint traditionally used rapidly frozen tissue [39] but a room temperature, molecular fixative is available for use within 60 minutes of obtaining fresh tissue samples. [75]

  9. Breast cancer management - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_management

    Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.