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The remainder of the serum cholesterol after subtracting the HDL is the non-HDL cholesterol. The concentration of these other components, which may cause atheroma , is known as the non-HDL-C . This is now preferred to LDL-C as a secondary marker as it has been shown to be a better predictor and it is more easily calculated.
Reverse cholesterol transport is a multi-step process resulting in the net movement of cholesterol from peripheral tissues back to the liver first via entering the lymphatic system, then the bloodstream. [1] HDL is first produced in the liver in a cholesterol-free form. As a result, it appears discoidal in shape.
[3] [104] Results may be expressed as "calculated", indicating a calculation of total cholesterol, HDL, and triglycerides. [3] Cholesterol is tested to determine for "normal" or "desirable" levels if a person has a total cholesterol of 5.2 mmol/L or less (200 mg/dL), an HDL value of more than 1 mmol/L (40 mg/dL, "the higher, the better"), an ...
High-density lipoprotein or HDL cholesterol, on the other hand, is sometimes called “good” cholesterol because it removes fats from your blood, Gersch says. A healthy HDL level is 60 or higher.
1071 n/a Ensembl ENSG00000087237 n/a UniProt P11597 n/a RefSeq (mRNA) NM_000078 NM_001286085 n/a RefSeq (protein) NP_000069 NP_001273014 n/a Location (UCSC) Chr 16: 56.96 – 56.98 Mb n/a PubMed search n/a Wikidata View/Edit Human Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and ...
High cholesterol is a risk factor for heart disease and stroke. But you might not even know you have it until a doctor runs a blood test. After all, high cholesterol doesn’t have any specific ...
Under certain abnormal physiological conditions such as system infection or sepsis, the major components of HDL become altered, [9] [10] The composition and quantity of lipids and apolipoproteins are altered as compared to normal physiological conditions, such as a decrease in HDL cholesterol (HDL-C), phospholipids, apoA-I (a major lipoprotein ...
For this reason, total LDL is referred to as "bad cholesterol," although only a fraction of it is actually bad. Standard chemistry panels typically include total triglyceride, LDL and HDL levels in the blood. Measuring the concentration of sd-LDL is expensive.