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6–67 million [ 2][ 4] Glaucoma is a group of eye diseases that lead to damage of the optic nerve, which transmits visual information from the eye to the brain. Glaucoma may cause vision loss if left untreated. It has been called the "silent thief of sight" because the loss of vision usually occurs slowly over a long period of time. [ 5]
Genetic. Diagnostic method. Slit lamp. Treatment. None. Stargardt disease is the most common inherited single-gene retinal disease. [ 1] In terms of the first description of the disease, [ 2] it follows an autosomal recessive inheritance pattern, which has been later linked to bi-allelic ABCA4 gene variants (STGD1).
1:30,000 to 1:50,000. Leber's hereditary optic neuropathy ( LHON) is a mitochondrially inherited (transmitted from mother to offspring) degeneration of retinal ganglion cells (RGCs) and their axons that leads to an acute or subacute loss of central vision; it predominantly affects young adult males. LHON is transmitted only through the mother ...
Secondary glaucoma is a collection of progressive optic nerve disorders associated with a rise in intraocular pressure (IOP) which results in the loss of vision. In clinical settings, it is defined as the occurrence of IOP above 21 mmHg requiring the prescription of IOP-managing drugs. [1] It can be broadly divided into two subtypes: secondary ...
Weill–Marchesani syndrome is a rare genetic disorder characterized by short stature; an unusually short, broad head ( brachycephaly) and other facial abnormalities; hand defects, including unusually short fingers ( brachydactyly ); and distinctive eye ( ocular) abnormalities. It was named after ophthalmologists Georges Weill (1866–1952) and ...
Glaucoma is an eye disease often characterized by increased pressure within the eye or intraocular pressure (IOP). [60] Glaucoma causes visual field loss as well as severs the optic nerve. [ 61 ] Early diagnosis and treatment of glaucoma in patients is imperative because glaucoma is triggered by non-specific levels of IOP. [ 61 ]
Pigment dispersion syndrome ( PDS) is an eye disorder that can lead to a form of glaucoma known as pigmentary glaucoma. It takes place when pigment cells slough off from the back of the iris and float around in the aqueous humor. Over time, these pigment cells can accumulate in the anterior chamber in such a way that they begin to clog the ...
Cataracts cause 51% of all cases of blindnessand 33% of visual impairmentworldwide. [3][9] Cataracts are most commonly due to agingbut may also occur due to traumaor radiation exposure, be present from birth, or occur following eye surgery for other problems. [1][4]Risk factors include diabetes, longstanding use of corticosteroidmedication ...
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