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Specialty. Ophthalmology. Internuclear ophthalmoplegia ( INO) is a disorder of conjugate lateral gaze in which the affected eye shows impairment of adduction. When an attempt is made to gaze contralaterally (relative to the affected eye), the affected eye adducts minimally, if at all. The contralateral eye abducts, however with nystagmus.
Neuromyelitis optica spectrum disorder. Myasthenia Gravis. The one and a half syndrome is a rare weakness in eye movement affecting both eyes, in which one cannot move laterally at all, and the other can move only in outward direction. More formally, it is characterized by " a conjugate horizontal gaze palsy in one direction and an internuclear ...
Parinaud's syndrome is a constellation of neurological signs indicating injury to the dorsal midbrain. More specifically, compression of the vertical gaze center at the rostral interstitial nucleus of medial longitudinal fasciculus (riMLF). It is a group of abnormalities of eye movement and pupil dysfunction and is named for Henri Parinaud [ 6 ...
Ophthalmoparesis refers to weakness (-paresis) or paralysis (-plegia) of one or more extraocular muscles which are responsible for eye movements. It is a physical finding in certain neurologic, ophthalmologic, and endocrine disease. Internal ophthalmoplegia means involvement limited to the pupillary sphincter and ciliary muscle.
Chronic progressive external ophthalmoplegia ( CPEO) is a type of eye disorder characterized by slowly progressive inability to move the eyes and eyebrows. [ 1] It is often the only feature of mitochondrial disease, in which case the term CPEO may be given as the diagnosis. In other people suffering from mitochondrial disease, CPEO occurs as ...
Because multiple sclerosis causes demyelination of the axons of the central nervous system, it can cause internuclear ophthalmoplegia when medial longitudinal fasciculus axons get demyelinated. [8] This presents as nystagmus and diplopia. [7] Other demyelinating diseases, as well as certain neoplasms and strokes, can also cause the same ...
Lesions to abducens nucleus or PPRF typically create an ipsilateral gaze palsy, while lesions to MLF typically cause Internuclear ophthalmoplegia, a type of horizontal gaze palsy in which the affected eye cannot adduct in conjugation with the contralateral eye during horizontal gaze, but convergence is preserved. [3]
Internuclear ophthalmoplegia is a disorder of conjugate lateral gaze. The affected eye shows impairment of adduction . The partner eye diverges from the affected eye during abduction, producing diplopia ; during extreme abduction, compensatory nystagmus can be seen in the partner eye.