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In 5% of breast cancer cases, there is a strong inherited familial risk. [10] Two autosomal dominant genes, BRCA1 and BRCA2, account for most of the cases of familial breast cancer. Women who carry a harmful BRCA mutation have a 60% to 80% risk of developing breast cancer in their lifetimes. [10]
This is an accepted version of this page This is the latest accepted revision, reviewed on 16 February 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...
Breast cancer incidence by age in women (UK) 2006-08 [21] Breast cancer is the most common cancer in the UK (around 56,000 women and 375 men are diagnosed with the disease every year). It is the fourth most common cause of cancer death (around 11,400 women and 85 men die each year) and the second most common cause of death in women. [22]
Breast density is associated with a 1.2 to four times higher risk of developing breast cancer Women unaware of important sign that indicates increased breast cancer risk, study finds Skip to main ...
For example, the daughters of women who have breast cancer have significantly higher levels of estrogen and progesterone than the daughters of women without breast cancer. These higher hormone levels may explain why these women have higher risk of breast cancer, even in the absence of a breast-cancer gene. [58]
Worldwide, breast cancer is the leading type of cancer in women, accounting for 25% of all cases. [5] It is most common in women over age 50. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. [6]
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