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“While arnica is considered safe to apply topically to the skin, it shouldn’t be taken as an oral supplement for inflammation, as it can cause serious side effects, including heart damage ...
Beyond adverse effects from the herb itself, "adulteration, inappropriate formulation, or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life threatening or lethal." [3]
Arnica montana: Arnica: Used as an anti-inflammatory [23] and for osteoarthritis. [24] The US Food and Drug Administration has classified Arnica montana as an unsafe herb because of its toxicity. [25] It should not be taken orally or applied to broken skin where absorption can occur. [25] Astragalus propinquus: Astragalus: Long used in ...
Arnica montana contains the toxin helenalin, which can be poisonous if large amounts of the plant are eaten or small amounts of concentrated Arnica are used. Consumption of A. montana can produce severe gastroenteritis , internal bleeding of the digestive tract, raised liver enzymes (which can indicate inflammation of the liver), nervousness ...
With multiple sclerosis, inflammation settles in the central nervous system after immune cells attack the coating on nerves; lupus can cause inflammation in the heart, brain, kidney, and other organs.
Helenalin, or (-)-4-Hydroxy-4a,8-dimethyl-3,3a,4a,7a,8,9,9a-octahydroazuleno[6,5-b]furan-2,5-dione, is a toxic sesquiterpene lactone which can be found in several plants such as Arnica montana and Arnica chamissonis Helenalin is responsible for the toxicity of the Arnica spp.
Anti-inflammatory or antiphlogistic is the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs , also called anti-inflammatories , make up about half of analgesics .
Chronic systemic inflammation is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system.It can contribute to the development or progression of certain conditions such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, autoimmune and neurodegenerative ...
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