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Chromosome 6 spans nearly 171 million base pairs (the building material of DNA) and represents between 5.5 and 6% of the total DNA in cells. It contains the major histocompatibility complex , which contains over 100 genes related to the immune response , and plays a vital role in organ transplantation .
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. [6] The function of IRF6 is related to the formation of connective tissue, for example that of the palate. [7]
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HLA region of Chromosome 6. The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. [1] The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. [2]
Human chromosome 6 gene stubs (415 P) Pages in category "Genes on human chromosome 6" The following 200 pages are in this category, out of approximately 779 total.
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HLA B7-DR15-DQ6 is a multigene haplotype that covers a majority of the human major histocompatibility complex on chromosome 6.A multigene haplotype is set of inherited alleles covering several genes, or gene-alleles, common multigene haplotypes are generally the result of descent by common ancestry (share a recent common ancestor for that segment of the chromosome).
Researchers on Wednesday unveiled the first complete sequence of the human Y chromosome, which is one of the two sex chromosomes - the X chromosome being the other - and is typically passed down ...
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