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Follicular hyperplasia (FH) is a type of lymphoid hyperplasia and is classified as a lymphadenopathy, which means a disease of the lymph nodes. It is caused by a stimulation of the B cell compartment and by abnormal cell growth of secondary follicles .
EBV-positive reactive lymphoid hyperplasia (or EBV-positive reactive lymphoid proliferation) is a benign form of lymphadenopathy, i.e. swollen, often painful lymph nodes. The disorder is based on histologic findings that occur in the lymphoid tissue of mainly older individuals who were infected with EBV many years earlier.
Lymphoid hyperplasia is the rapid proliferation of normal lymphocytic cells that resemble lymph tissue which may occur with bacterial or viral infections. [1] The growth is termed hyperplasia which may result in enlargement of various tissue including an organ, or cause a cutaneous lesion .
Most cases of reactive follicular hyperplasia are easy to diagnose, but some cases may be confused with follicular lymphoma. There are seven distinct patterns of benign lymphadenopathy: [6] Follicular hyperplasia: This is the most common type of reactive lymphadenopathy. [6]
Feline diseases are often opportunistic and tend to be more serious in cats that already have concurrent sicknesses. Some of these can be treated and the animal can have a complete recovery. Others, like viral diseases, are more difficult to treat and cannot be treated with antibiotics, which are not effective against viruses.
Lymphoma, a cancer of the immune system, can also present with swollen tonsils: “It can be on one or both sides, often with lumps or lymph nodes in the neck, armpits, or groin,” says Dr. Zalvan.
Lingual tonsils are covered externally by stratified squamous epithelium (nonkeratinized) that invaginates inward forming tonsillar crypts. Beneath the epithelium is a layer of lymphoid nodules containing lymphocytes. Mucous glands located at the root of the tongue are drained through several ducts into the crypts of the lingual tonsils.
Similar signs and symptoms can be found in diseases such partial choanal atresia and significant palatine tonsil hyperplasia. Nasal airway blockage can also result from endonasal foreign bodies, nasal concha hyperplasia, and allergic or viral rhinitis. Neoplasms that are benign or malignant in particular need to be ruled out.