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Follicular hyperplasia (FH) is a type of lymphoid hyperplasia and is classified as a lymphadenopathy, which means a disease of the lymph nodes. It is caused by a stimulation of the B cell compartment and by abnormal cell growth of secondary follicles .
EBV-positive reactive lymphoid hyperplasia (or EBV-positive reactive lymphoid proliferation) is a benign form of lymphadenopathy, i.e. swollen, often painful lymph nodes. The disorder is based on histologic findings that occur in the lymphoid tissue of mainly older individuals who were infected with EBV many years earlier.
Lymphoid hyperplasia is the rapid proliferation of normal lymphocytic cells that resemble lymph tissue which may occur with bacterial or viral infections. [1] The growth is termed hyperplasia which may result in enlargement of various tissue including an organ, or cause a cutaneous lesion .
Histopathology of diffuse large B-cell lymphoma occurring in the tonsil. H&E stain. Lymphoproliferative disorders (LPDs) refer to a specific class of diagnoses, comprising a group of several conditions, in which lymphocytes are produced in excessive quantities. These disorders primarily present in patients who have a compromised immune system.
Castleman diseases; Other names: Giant lymph node hyperplasia, lymphoid hamartoma, angiofollicular lymph node hyperplasia: Micrograph of Castleman disease showing hyaline vascular features including atrophic germinal center, expanded mantle zone, and a radially penetrating sclerotic blood vessel ("lollipop" sign).
The clinical and anatomic basis of hypertrophy is the enlargement of the germinal centers of lymphoid tissue and lymphoid follicles. The fundamental reason is thought to be a vicious cycle of inflammation, hypertrophy and/or hyperplasia, secretory retention, and recurrent inflammation. [1]
The mucosa-associated lymphoid tissue (MALT), also called mucosa-associated lymphatic tissue, is a diffuse system of small concentrations of lymphoid tissue found in various submucosal membrane sites of the body, such as the gastrointestinal tract, nasopharynx, thyroid, breast, lung, salivary glands, eye, and skin.
Lingual tonsils are covered externally by stratified squamous epithelium (nonkeratinized) that invaginates inward forming tonsillar crypts. Beneath the epithelium is a layer of lymphoid nodules containing lymphocytes. Mucous glands located at the root of the tongue are drained through several ducts into the crypts of the lingual tonsils.