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A bone tumor is an abnormal growth of tissue in bone, traditionally classified as noncancerous (benign) or cancerous (malignant). [1] [4] Cancerous bone tumors usually originate from a cancer in another part of the body such as from lung, breast, thyroid, kidney and prostate. [1] There may be a lump, pain, or neurological signs from pressure. [1]
If the tumor is large, there may be pain over the affected area, a pathological fracture, and the affected limb might not function properly. [1] It can occur as part of a syndrome such as when multiple non-ossifying fibromas occur in neurofibromatosis , or Jaffe–Campanacci syndrome in combination with cafe-au-lait spots , mental retardation ...
Osteochondroma is the most common benign tumor of bone. [1] [2] The tumors take the form of cartilage-capped bony projections or outgrowth on the surface of bones . [3] [4] It is characterized as a type of overgrowth that can occur in any bone where cartilage forms bone. Tumors most commonly affect long bones around the knee and in the forearm.
Ewing’s sarcoma of bone is the most common of the EFTs and tends to occur in the trunk and long bones. The cancer most often occurs in the shaft, or diaphysis, of bones, as compared to other common bone cancers. The most common presenting symptom is pain in the bone, and the initial diagnostic step is imaging, often both MRI and radiograph.
The diaphysis (pl.: diaphyses) is the main or midsection (shaft) of a long bone. It is made up of cortical bone and usually contains bone marrow and adipose tissue (fat). It is a middle tubular part composed of compact bone which surrounds a central marrow cavity which contains red or yellow marrow. In diaphysis, primary ossification occurs.
Ollier disease is a rare sporadic nonhereditary skeletal disorder in which typically benign cartilaginous tumors (enchondromas) develop near the growth plate cartilage. This is caused by cartilage rests that grow and reside within the metaphysis or diaphysis and eventually mineralize over time to form multiple enchondromas. [ 1 ]
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Camurati–Engelmann disease (CED) is a very rare autosomal dominant genetic disorder that causes characteristic anomalies in the skeleton. It is also known as progressive diaphyseal dysplasia. It is a form of dysplasia. [3] Patients typically have heavily thickened bones, especially along the shafts of the long bones (called