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Hypertrophic Osteodystrophy (HOD) is a bone disease that occurs most often in fast-growing large and giant breed dogs; however, it also affects medium breed animals like the Australian Shepherd. The disorder is sometimes referred to as metaphyseal osteopathy , and typically first presents between the ages of 2 and 7 months. [ 1 ]
Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. Distal expansion of the long bones as well as painful, swollen joints [ 3 ] and synovial villous proliferation are often seen.
Panosteitis, sometimes shortened to pano among breeders, [1] is an occasionally seen long bone condition in large breed dogs.It manifests with sudden, unexplained pain and lameness that may shift from leg to leg, usually between 5 and 14 months of age, earning the nickname "growing pains. "[2] Signs such as fever, weight loss, anorexia, and lethargy can also be seen.
Albright's hereditary osteodystrophy; Albright's hereditary osteodystrophy has an autosomal dominant pattern of inheritance: Specialty: Endocrinology Symptoms: Choroid plexus calcification, Full cheeks [1] Causes: Gs alpha subunit deficiency [2] Diagnostic method: calcium, phosphorus, PTH, Urine test for phosphorus and cyclic AMP: Treatment
Other names are primary hypertrophic osteoarthropathy or Touraine-Solente-Golé syndrome. [2] It is mainly characterized by pachyderma (thickening of the skin), periostosis (excessive bone formation) and finger clubbing (swelling of tissue with loss of normal angle between nail and nail bed).
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Symptoms include stiffness and warm, firm swelling of the legs, and signs of lung disease such as coughing and difficulty breathing. Hypertrophic osteopathy in humans differs from a similar condition in dogs, in that in humans it is usually caused by lung tumors or infections such as Mycobacterium fortuitum or Corynebacterium .
All forms of renal osteodystrophy should also be distinguished from other bone diseases which may equally result in decreased bone density (related or unrelated to CKD): osteoporosis [19] osteopenia [20] osteomalacia [21] brown tumor should be considered as the top-line diagnosis if a mass-forming lesion is present. [22] [23]