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Multifactorial disorders exhibit a combination of distinct characteristics which are clearly differentiated from Mendelian inheritance. The risk of multifactorial diseases may get increased due to environmental influences. The disease is not sex-limited but it occurs more frequently in one gender than the other; females are more likely to have ...
Genetic disorders may also be complex, multifactorial, or polygenic, meaning they are likely associated with the effects of multiple genes in combination with lifestyles and environmental factors. Multifactorial disorders include heart disease and diabetes. Although complex disorders often cluster in families, they do not have a clear-cut ...
If multifactorial inheritance is indeed the case, then the chance of the patient contracting the disease is reduced only if cousins and more distant relatives have the disease. [13] While multifactorially-inherited diseases tend to run in families, inheritance will not follow the same pattern as a simple monohybrid or dihybrid cross. [10]
Multifactorial (having many factors) can refer to: The multifactorial in mathematics. Multifactorial inheritance , a pattern of predisposition for a disease process.
The following is a list of genetic disorders and if known, type of mutation and for the chromosome involved. Although the parlance "disease-causing gene" is common, it is the occurrence of an abnormality in the parents that causes the impairment to develop within the child. There are over 6,000 known genetic disorders in humans.
Genetic disorders may be grouped into single-gene defects, multiple-gene disorders, or chromosomal defects. Single-gene defects may arise from abnormalities of both copies of an autosomal gene (a recessive disorder) or of only one of the two copies (a dominant disorder). Some conditions result from deletions or abnormalities of a few genes ...
Depression is primarily a human condition described by the World Health Organization as a low mood or loss of pleasure or interest in activities for long periods of time. In people, it results ...
The most consistent and dramatic evidence of family influences on cardiovascular disease (CVD) is family aggregation of physiological factors. In several studies the parent-child and sibling-sibling correlations of blood pressure are approximately .24. Genetic determination of blood pressure is strong, but does not explain all of the variance.