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Temsirolimus is a specific inhibitor of mTOR and interferes with the synthesis of proteins that regulate proliferation, growth, and survival of tumor cells. Though temsirolimus shows activity on its own, it is also known to be converted to sirolimus (rapamycin) in vivo; [4] therefore, its activity may be more attributed to its metabolite rather than the prodrug itself (despite claims to the ...
In the European Union, the European Medicines Agency has jurisdiction and the relevant documents are called the "summary of product characteristics" (SPC or SmPC) and the document for end-users is called the "patient information leaflet" or "package leaflet". The SPC is not intended to give general advice about treatment of a condition but does ...
mTOR inhibitors are a class of drugs used to treat several human diseases, including cancer, autoimmune diseases, and neurodegeneration. They function by inhibiting the mammalian target of rapamycin (mTOR) (also known as the mechanistic target of rapamycin), which is a serine/threonine-specific protein kinase that belongs to the family of phosphatidylinositol-3 kinase (PI3K) related kinases ...
The US retail price of etanercept has risen over time. In 2008, the cost of etanercept was $1,500 per month or $18,000 per year. [ 50 ] By 2011, the cost had exceeded $20,000 per year.
The National Research Centre is an Egyptian research and development center for multiple disciplines including agriculture, chemistry, biology, medicine, engineering and genetics. [1]
This image is a map derived from a United Nations map. Unless stated otherwise, UN maps are to be considered in the public domain. This applies worldwide. Some UN maps have special copyrights, as indicated on the map itself. UN maps are, in principle, open source material and you can use them in your work or for making your own map.
Lake Moeris (Ancient Greek: Μοῖρις, genitive Μοίριδος) was an ancient endorheic freshwater lake located in the Faiyum Oasis, 80 km (50 mi) southwest of Cairo, Egypt, which persists today at a fraction of its former size as the hypersaline Lake Qarun (Arabic: بركة قارون).
Largest cities See also Further reading External links 0-9 10th of Ramadan 15th of May 6th of October A Abu El Matamir Abu Hummus Abu Tesht Abu Tig Akhmim Al Khankah Alexandria Arish Ashmoun Aswan Awsim Ain El Sokhna B Badr Baltim Banha Basyoun Biyala Belqas Beni Mazar Beni Suef Beni Ebeid Biba Bilbeis Birket El Sab Borg El Arab Borg El Burullus Bush C Cairo D Dahab Dairut Damanhur Damietta ...