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Premalignant lesions are morphologically atypical tissue which appear abnormal when viewed under the microscope, and which are more likely to progress to cancer than normal tissue. [7] Precancerous conditions and lesions affect a variety of organ systems, including the skin, oral cavity, stomach, colon, lung, and hematological system.
A premalignant (or precancerous) lesion is defined as "a benign, morphologically altered tissue that has a greater than normal risk of malignant transformation." There are several different types of premalignant lesion that occur in the mouth.
Oral leukoplakia is a potentially malignant disorder affecting the oral mucosa. It is defined as "essentially an oral mucosal white/gray lesion that cannot be considered as any other definable lesion." Oral leukoplakia is a gray patch or plaque that develops in the oral cavity and is strongly associated with smoking. [8]
The lesion is a white patch, which almost exclusively occurs on the lateral surfaces of the tongue, although rarely it may occur on the buccal mucosa, soft palate, pharynx or esophagus. [5] The lesion may grow to involve the dorsal surface of the tongue. The texture is vertically corrugated ("hairy") or thickly furrowed and shaggy in appearance.
Early lesions may appear as thin, translucent and granular or wrinkled mucosa. [2] [6] The later lesion may appear thicker, more opaquely white and hyperkeratotic with fissures and folds. [6] [2] Oral snuff causes more pronounced changes in the oral mucosa than tobacco chewing. [1] Snuff dipping is associated more with verrucous keratosis. [1]
Oral submucous fibrosis is clinically divided into three stages: [24] Stage 1: Stomatitis; Stage 2: Fibrosis a. Early lesions, blanching of the oral mucosa; b. Older lesions, vertical and circular palpable fibrous bands in and around the mouth or lips, resulting in a mottled, marble-like appearance of the buccal mucosa
Prado also says you should avoid buccal if you've had facial or waxing treatments within 7 to 14 days, have cancerous moles or lesions with suspected malignancy, have open cold sores, an active ...
Squamous cell papilloma of the mouth or throat is generally diagnosed in people between the ages of 30 and 50, [1] and is normally found on the inside of the cheek, on the tongue, or inside of lips. Oral papillomas are usually painless, and not treated unless they interfere with eating or are causing pain. [ 1 ]