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A diuretic (/ ˌ d aɪ j ʊ ˈ r ɛ t ɪ k /) is any substance that promotes diuresis, the increased production of urine. This includes forced diuresis. A diuretic tablet is sometimes colloquially called a water tablet. There are several categories of diuretics. All diuretics increase the excretion of water from the body, through the kidneys ...
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This is an accepted version of this page This is the latest accepted revision, reviewed on 29 January 2025. Cloud-based presentation software Google Slides An example of a Google Slides presentation Developer(s) Google LLC Initial release March 9, 2006 ; 18 years ago (2006-03-09) Stable release(s) [±] Android 1.25.042.02 / 27 January 2025 ; 5 days ago (2025-01-27) iOS 1.2025.04201 / 27 ...
Thiazide diuretics inhibit this receptor, causing the body to release NaCl and water into the lumen, thereby increasing the amount of urine produced each day. [6] An example of a molecule that is chemically a thiazide but not used as a diuretic is methylchloroisothiazolinone , often found as an antimicrobial in cosmetics.
WHODrug concepts can be organized into groups. Standardised Drug Groupings (SDGs) define groups of drugs. For example, diuretics, corticosteroids, drugs used in diabetes. Groups are also defined based on interaction, for example, drugs interacting with CYP2C8 or drugs interacting with UGT. R,Lee [4]
Potassium-sparing diuretics or antikaliuretics [1] refer to drugs that cause diuresis without causing potassium loss in the urine. [2] They are typically used as an adjunct in management of hypertension , cirrhosis , and congestive heart failure . [ 3 ]
The tendency, as for all loop diuretics, to cause low serum potassium concentration (hypokalemia) has given rise to combination products, either with potassium or with the potassium-sparing diuretic amiloride (Co-amilofruse). Other electrolyte abnormalities that can result from furosemide use include hyponatremia, hypochloremia, hypomagnesemia ...
This observation was the basis for the discovery and development of modern diuretic drugs. Frederic Bartter (1914–1983) worked on hormones affecting the kidney that led to the discovery of syndrome of inappropriate antidiuretic hormone (SIADH) in 1957 and Bartter syndrome in 1963. Schwartz-Bartter syndrome is named after these two scientists.
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