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List of free analog and digital electronic circuit simulators, available for Windows, macOS, Linux, and comparing against UC Berkeley SPICE. The following table is split into two groups based on whether it has a graphical visual interface or not.
A schematic of a patch clamp chip showing a gigaseal, whole cell recording configuration, and the ion channel and whole cell currents. Many types of systems have been developed for patch clamping cells in suspension cultures. One system uses a traditional pipette and cells in a droplet suspension culture to obtain patch clamp recordings (see ...
Alternatively, the current clamp technique can be used. In this case, the current passing across the membrane is controlled by the experimenter and the resulting changes in voltage are recorded, generally in the form of action potentials. Erwin Neher and Bert Sakmann developed the patch clamp in the late 1970s and early 1980s. This discovery ...
An electrical meter with integral AC current clamp is known as a clamp meter, clamp-on ammeter, tong tester, or colloquially as an amp clamp. A clamp meter measures the vector sum of the currents flowing in all the conductors passing through the probe, which depends on the phase relationship of the currents. Only one conductor is normally ...
The current clamp technique records the membrane potential by injecting current into a cell through the recording electrode. Unlike in the voltage clamp mode, where the membrane potential is held at a level determined by the experimenter, in "current clamp" mode the membrane potential is free to vary, and the amplifier records whatever voltage ...
Sim4Life.lite - online version of Sim4Life that is free-of-charge for students for team-learning and online collaboration with classmates and teachers on limited size projects. Simantics System Dynamics – used for modelling and simulating large hierarchical models with multidimensional variables created in a traditional way with stock and ...
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Voltage and current errors: SEV-c circuitry does not actually measure the voltage of the cell being clamped (as does a two-electrode clamp). The patch-clamp amplifier is like a two-electrode clamp, except the voltage measuring and current passing circuits are connected (in the two-electrode clamp, they are connected through the cell). The ...