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The amidohydrolase superfamily is a large protein family of more than 20,000 members with diverse chemistry and physiologic roles. Due to its complexity and size, the amidohydrolase superfamily is being used by the Enzyme Function Initiative (EFI) for developing a large-scale strategy for functional assignment of unknown proteins.
General structure of an amide (specifically, a carboxamide) Formamide, the simplest amide Asparagine (zwitterionic form), an amino acid with a side chain (highlighted) containing an amide group. In organic chemistry, an amide, [1] [2] [3] also known as an organic amide or a carboxamide, is a compound with the general formula R−C(=O)−NR′R ...
Peptide bond formation via dehydration reaction. When two amino acids form a dipeptide through a peptide bond, [1] it is a type of condensation reaction. [2] In this kind of condensation, two amino acids approach each other, with the non-side chain (C1) carboxylic acid moiety of one coming near the non-side chain (N2) amino moiety of the other.
General structure of a thioamide. A thioamide (rarely, thionamide, but also known as thiourylenes) is a functional group with the general structure R 1 −C(=S)−NR 2 R 3, where R 1, R 2 and R 3 are any groups (typically organyl groups or hydrogen).
Peptides are short chains of amino acids linked by peptide bonds. [1] [2] A polypeptide is a longer, continuous, unbranched peptide chain. [3] Polypeptides that have a molecular mass of 10,000 Da or more are called proteins. [4] Chains of fewer than twenty amino acids are called oligopeptides, and include dipeptides, tripeptides, and tetrapeptides.
In organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds. Peptides are chemically synthesized by the condensation reaction of the carboxyl group of one amino acid to the amino group of another.
The different types of lipid-linked oligosaccharide (LLO) precursor produced in different organisms.. N-linked glycosylation is the attachment of an oligosaccharide, a carbohydrate consisting of several sugar molecules, sometimes also referred to as glycan, to a nitrogen atom (the amide nitrogen of an asparagine (Asn) residue of a protein), in a process called N-glycosylation, studied in ...
Structures of three kinds of amides: an organic amide (carboxamide), a sulfonamide, and a phosphoramide. In chemistry, the term amide (/ ˈ æ m aɪ d / or / ˈ æ m ɪ d / or / ˈ eɪ m aɪ d /) [1] [2] [3] is a compound with the functional group R n E(=O) x NR 2, where x is not zero, E is some element, and each R represents an organic group or hydrogen. [4]