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[81] [82] [83] [53] [84] A dosage of oral norethisterone of 25 mg/day for 3 weeks in men has been reported to suppress testosterone levels by about 70%, to 100 to 200 ng/dL, within 4 or 5 days, as well as to suppress sperm count and to have no effect on libido or erectile function over this short time period.
Norethisterone and ethinylestradiol levels over 24 hours after a single oral dose of 10 mg NETA in postmenopausal women. [25] NETA metabolizes into ethinylestradiol at a rate of 0.20 to 0.33% across a dose range of 10 to 40 mg. [26] [27] Peak levels of ethinylestradiol with a 10, 20, or 40 mg dose of NETA were 58, 178, and 231 pg/mL, respectively.
Any brand of combined oral contraceptive pills can be used in an extended or continuous manner by simply discarding the placebo pills; this is most commonly done with monophasic pills in which all of the pills in a package contain the same fixed dosing of a synthetic estrogen and a progestin in each active pill. [3]
Progestogens have been found to maximally suppress circulating testosterone levels in men by up to 70 to 80% at sufficiently high doses. [ 219 ] [ 220 ] This is notably less than that achieved by GnRH analogues , which can effectively abolish gonadal production of testosterone and suppress circulating testosterone levels by as much as 95%. [ 221 ]
All contain an estrogen, ethinylestradiol or mestranol, [1] [2] in varying amounts, and one of a number of different progestogens. (Regarding the estrogen, the inactive 3-methyl ether of ethinylestradiol, which must be metabolized by the liver into the active ethinylestradiol; 50 μg of mestranol is equivalent to only 35 μg of ethinylestradiol and should not be used when high-dose [50 μg ...
Norgestrel (Opill) – 0.075 mg (available over-the-counter as of 2023) [43] Norgestrel (Ovrette; 0.075 mg) was also previously available in the U.S. as a prescription, but was discontinued in 2005 due to "marketing reasons".
Rhino pills may work, in theory — some of the purported ingredients can increase blood flow to the privates. But in practice, they’re not considered medically reliable — or safe.
Mestranol/norethisterone (brand names Norethin, Noriday, Norinyl, Norquen, Ortho-Novum, others) is a combination of the estrogen ethinylestradiol and the progestin norethisterone (norethindrone) which was introduced in 1963 and was the second combined oral contraceptive to be marketed, following mestranol/noretynodrel in 1960. [1]
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