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Current Cancer Drug Targets is a peer-reviewed medical journal published by Bentham Science Publishers.The editor-in-chief is Ruiwen Zhang (UH Drug Discovery Institute). The journal covers research on contemporary molecular drug targets involved in cancer, including medicinal chemistry, pharmacology, molecular biology, genomics, and biochemistry.
The American Society of Health-System Pharmacists (ASHP) reported that 323 "active medication shortages" were reported in January–March 2024. As a result of drug scarcity, many healthcare systems were forced to either ration out essential drugs, triage patients based on the severity of their condition and their need for the drug, or both.
Target validation normally requires the determination that the target is expressed in the disease-relevant cells/tissues, [6] it can be directly modulated by a drug or drug-like molecule with adequate potency in biochemical assay, [7] and that target modulation in cell and/or animal models ameliorates the relevant disease phenotype. [8]
Each DrugCard entry (Fig. 1) contains more than 200 data fields with half of the information being devoted to drug/chemical data and the other half devoted to drug target or protein data. [ 4 ] Four additional databases, HMDB, [ 5 ] T3DB, [ 6 ] SMPDB [ 7 ] and FooDB are also part of a general suite of metabolomic / cheminformatic databases.
In this context, the biological target is often referred to as a drug target. The most common drug targets of currently marketed drugs include: [4] [5] [6] proteins G protein-coupled receptors (target of 50% of drugs) [7] enzymes (especially protein kinases, proteases, esterases, and phosphatases) ion channels ligand-gated ion channels
Journal of Drug Targeting is a peer-reviewed medical journal published by Informa that covers research on all aspects of drug delivery and drug targeting for molecular and macromolecular drugs. The editor in chief is Saghir Akhtar (College of Medicine, Qatar University ).
Drug Target Insights is a peer-reviewed open access academic journal focusing on drug treatment targets and clinical therapeutics. The journal was founded in 2006 by Monica Milani and is currently edited by Giulio Zuanetti .
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