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Foal immunodeficiency syndrome (FIS), originally known as Fell pony syndrome, mainly affects two breeds of ponies: the Fell and Dales. FIS is a recessive genetic disease . Affected foals appear normal at birth, but become weak, and either die or must be euthanized by three months of age due to persistent infections caused by immunodeficiency.
The disease has a similar cause to Hirschsprung's disease in humans. A mutation in the middle of the endothelin receptor type B ( EDNRB ) gene causes lethal white syndrome when homozygous . Carriers, which are heterozygous —that is, have one copy of the mutated allele , but themselves are healthy—can now be reliably identified with a DNA test .
The Belgian Draft Horse is one breed in which JEB occurs. Junctional epidermolysis bullosa (JEB) is an inherited disorder that is also known as red foot disease or hairless foal syndrome. [1] JEB is the result of a genetic mutation that inhibits protein production that is essential for skin adhesion. [2]
An equine malocclusion is a misalignment between the upper and lower jaws of a horse or other equine. It results in a faulty bite with the upper and lower teeth failing to meet correctly. [1] Malocclusions can cause pain to the horse and may also lead to weight loss and other eating problems related to poor chewing or loss of appetite.
Some horse organizations have instituted rules to attempt to eliminate this widespread disease. The American Quarter Horse Association (AQHA) mandates testing for foals descended from Impressive if both of the foal's parents were not homozygous negative (N/N) for the gene, [2] and, since 2007, has not registered foals homozygous (H/H) for the ...
Naked foal syndrome (NFS) is a genetic disorder specific to the Akhal-Teke horse breed. A rare genodermatosis, it is characterized by almost complete hairlessness and mild ichthyosis. The condition is inherited as a monogenic autosomal recessive trait, and affected horses typically die between a few weeks and three years of age. The exact cause ...
Horse cribbing is an unwanted behavior among horse owners because it can lead to various physical problems. Horses that crib may cause damage to their teeth due to excessive wear.
The cause of wry nose in horses is unknown; it may have a genetic cause, or be due to malpositioning in the uterus. [1] A wry nose may cause difficulty during foaling (dystocia). [3] A foal with wry nose may have poor alignment (malocclusion) of the teeth, [2] although foals can usually still nurse and in most cases are bright and active. [4]