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Ezetimibe/atorvastatin (trade names Liptruzet, Atozet) is a cholesterol lowering combination drug.In the United States, it was approved in May 2013, by the Food and Drug Administration for the treatment of elevated low-density lipoprotein (LDL) in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet. [1]
Level of the good cholesterol HDL is also increased. Fibrates may decrease LDL, though generally to a lesser degree than statins. Similar to statins, the risk of muscle damage exists. Nicotinic acid, like fibrates, is also well suited for lowering triglycerides by 20–50%. It may also lower LDL by 5–25% and increase HDL by 15–35%.
What's most important is to get blood cholesterol to healthy levels, whether by taking a statin or bempedoic acid or other lipid-lowering medication, Nissen said in an interview. LDL, or low ...
This article showcases a curated list of standout studies over the last week on topics such as cholesterol, GLP-1 drugs for weight loss, and supplements for heart health.
However, data (post hoc analysis) on atorvastatin has revealed that it may still be beneficial in reducing combined cardiac events, cardiac and all-cause mortality in those with a higher baseline LDL cholesterol >3.75 mmol/L. [50] [unreliable medical source] While the SHARP study suggested that LDL cholesterol-lowering treatments (e.g. statin ...
Research into next-generation cholesterol drugs is picking up. Source: Wikimedia Commons. Once upon a time in a regulatory environment far, far away, there was a cholesterol-fighting drug named ...
After three months, LDL cholesterol levels were reduced by 23% in participants taking bempedoic acid in addition to ezetimibe compared with an increase of around 5% in participants taking placebo and ezetimibe. [2] A phase III study found that bempedoic acid/ezetimibe lowered LDL-C by 39.2% compared to placebo in patients not taking statins. [7]
Berberine has potential benefits for heart health, such as lowering triglycerides (fat in the blood), total and LDL cholesterol, and systolic blood pressure, says Dr. Lona Sandon, PhD, RDN, LD, a ...
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