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The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...
In pharmacology, the international unit (IU) is a unit of measurement for the effect or biological activity of a substance, for the purpose of easier comparison across similar forms of substances. International units are used to quantify vitamins and biologics ( hormones , some medications , vaccines , blood products and similar biologically ...
Vitamin D 3 (cholecalciferol) is produced industrially by exposing 7-dehydrocholesterol to UVB and UVC light, followed by purification. The 7-dehydrocholesterol is sourced as an extraction from lanolin, a waxy skin secretion in sheep's wool. [203] Vitamin D 2 (ergocalciferol) is produced in a similar way using ergosterol from yeast as a ...
Ergocalciferol, also known as vitamin D 2 and nonspecifically calciferol, is a type of vitamin D found in food. It is used as a dietary supplement [ 3 ] to prevent and treat vitamin D deficiency [ 4 ] due to poor absorption by the intestines or liver disease . [ 5 ]
Because vitamin D is fat-soluble, it is hypothesized that absorption would be improved if patients are instructed to take their supplement with a meal. Raimundo et al. [73] [74] performed different studies confirming that a high-fat meal increased the absorption of vitamin D3 as measured by serum 25(OH) D. A clinical report indicated that serum ...
Vitamin D toxicity, ... (mcg or μg) and International Units (IU) ... with acute baits containing 3,000,000 IU/g for D3 and 4,000,000 IU/g for D2. This leads to ...
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