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Hepatic veno-occlusive disease (VOD) or veno-occlusive disease with immunodeficiency is a potentially life-threatening condition in which some of the small veins in the liver are obstructed. It is a complication of high-dose chemotherapy given before a bone marrow transplant or excessive exposure to hepatotoxic pyrrolizidine alkaloids .
Defibrotide, sold under the brand name Defitelio, is a mixture of single-stranded oligonucleotides that is purified from the intestinal mucosa of pigs. It is used to treat veno-occlusive disease of the liver of people having had a bone marrow transplant, with different limitations in the US and the European Union.
Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary hypertension caused by progressive blockage of the small veins in the lungs. [2] The blockage leads to high blood pressures in the arteries of the lungs, which, in turn, leads to heart failure .
Survival rates in Budd–Chiari syndrome after liver transplantation are 76%, 71% and 68% after 1, 5 and 10 years respectively. [2] It is recommended to continue anticoagulant treatment after liver transplantation, especially if the secondary or primary cause of hypercoagulability is still present, and to monitor for blood clots after liver ...
After Heart Transplant, New York Mom Finds Love in Cardiac Unit on Valentine's Day: 'Don't Ever Give Up' (Exclusive) Wendy Grossman Kantor. February 11, 2025 at 12:44 PM.
Former NBA star Nate Robinson received a kidney transplant nearly 20 years after he was diagnosed with kidney disease. Robinson announced that was scheduled to have the procedure later that day in ...
Liver transplantation is a potential treatment for acute or chronic conditions which cause irreversible and severe ("end-stage") liver dysfunction. [4] Since the procedure carries relatively high risks, is resource-intensive, and requires major life modifications after surgery, it is reserved for dire circumstances.
Carol Smith remembers the last-ever phone conversation she had with her son, Randall “Randy” Miod, a 55-year-old Malibu, Calif., resident, on Tuesday, Jan. 7 — the day the Pacific Palisades ...