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Microvascular decompression (MVD), also known as the Jannetta procedure, [1] is a neurosurgical procedure used to treat trigeminal neuralgia (along with other cranial nerve neuralgias), a pain syndrome characterized by severe episodes of intense facial pain, and hemifacial spasm.
Trigeminal neuralgia (TN or TGN), also called Fothergill disease, tic douloureux, trifacial neuralgia, is a long-term pain disorder that affects the trigeminal nerve, [6] [1] the nerve responsible for sensation in the face and motor functions such as biting and chewing.
An alternative to a decompression is a nerve ... The treatment of each peripheral nerve entrapment has ... Janetta procedure for trigeminal neuralgia [61] 1989: ...
The trigeminal nerve.. ATN is usually attributed to inflammation or demyelination, with increased sensitivity of the trigeminal nerve.These effects are believed to be caused by infection, demyelinating diseases, or compression of the trigeminal nerve (by an impinging vein or artery, a tumor, dental trauma, accidents, or arteriovenous malformation) and are often confused with dental problems.
Gabapentin is recommended as a first-line treatment for chronic neuropathic pain by various medical authorities. [10] [11] [31] [32] This is a general recommendation applicable to all neuropathic pain syndromes except for trigeminal neuralgia, where it may be used as a second- or third-line agent. [11] [32]
Vixotrigine (INN Tooltip International Nonproprietary Name, USAN Tooltip United States Adopted Name), formerly known as raxatrigine (INN Tooltip International Nonproprietary Name, USAN Tooltip United States Adopted Name), is an analgesic which is under development by Convergence Pharmaceuticals for the treatment of lumbosacral radiculopathy (sciatica) and trigeminal neuralgia (TGN).
Carbamazepine is most commonly prescribed to treat trigeminal neuralgia due to clinical experience and early clinical trials showing strong efficacy. Gabapentin may reduce symptoms associated with neuropathic pain or fibromyalgia in some people. [ 26 ]
Trigeminal neuralgia is a unilateral headache syndrome, [40] ... Lithium, methysergide, and topiramate are recommended alternative treatments, [49] [55] ...