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Anti-streptolysin O (ASO or ASLO) is the antibody made against streptolysin O, an immunogenic, oxygen-labile streptococcal hemolytic exotoxin produced by most strains of group A and many strains of groups C and G Streptococcus bacteria. The "O" in the name stands for oxygen-labile; the other related toxin being oxygen-stable streptolysin-S.
Streptolysin O (SLO; slo), is a bacterial toxin that has four protein domains which is known to make the plasma membranes in animal cells permeable. It does this by creating pore complexes within the membrane by first binding a monomer to the cholesterol found in the target membrane and then forming an oligomeric transmembrane pore. [6]
Antisense therapy is a form of treatment that uses antisense oligonucleotides (ASOs) to target messenger RNA (mRNA). ASOs are capable of altering mRNA expression through a variety of mechanisms, including ribonuclease H mediated decay of the pre-mRNA, direct steric blockage, and exon content modulation through splicing site binding on pre-mRNA. [1]
The human disease sickle cell anemia is caused by a genetic mutation in the codon for the sixth amino acid of the blood protein beta-hemoglobin. The normal DNA sequence G-A-G codes for the amino acid glutamate , while the mutation changes the middle adenine to a thymine , leading to the sequence G-T-G (G-U-G in the mRNA ).
The US doesn't run a surplus like most sovereign wealth funds. But Trump's order refers to trillions in existing assets.
Thinning blood and therefore making clots less likely is a definite pro for those who are at higher risk of cardiovascular issues. But that doesn't make aspirin a prime candidate for everyone.
When Keith Bussey first opened his Nothing Bundt Cakes location in Northern California in 2019, he exhausted his 401(k) savings, excited to invest in an up-and-coming franchise. And it really ...
Group A streptococcal infections are a number of infections with Streptococcus pyogenes, a group A streptococcus (GAS). [1] S. pyogenes is a species of beta-hemolytic Gram-positive bacteria that is responsible for a wide range of infections that are mostly common and fairly mild.