Search results
Results from the WOW.Com Content Network
Tetrahydrofuran (THF), or oxolane, is an organic compound with the formula (CH 2) 4 O. The compound is classified as heterocyclic compound , specifically a cyclic ether . It is a colorless, water- miscible organic liquid with low viscosity .
Furoic acid is reduced to tetrahydro-2-furoic acid, as originally reported in 1913 by Wienhaus. [4] Tetrahydro-2-furoic acid has been prepared via selective hydrogenation of 2-furoic acid over a bimetallic catalyst of palladium-nickel supported on alumina.
Common ether ligands are diethyl ether and tetrahydrofuran. Common chelating ether ligands include the glymes, dimethoxyethane (dme) and diglyme, and the crown ethers. Being lipophilic, metal-ether complexes often exhibit solubility in organic solvents, a property of interest in synthetic chemistry.
For example, tetrahydrofuran-3-one (3-ketotetrahydrofuran) [12] and 3-aminotetrahydrofuran [13] have been synthesized from 3-hydroxytetrahydrofuran and used in pharmaceutical syntheses. Additionally, additive amounts (0.05-0.15 weight %) of the nitrate ester manufactured by sulfuric acid - nitric acid nitration of 3-hydoxytetrahydrofuran have ...
The Feist–Benary synthesis is a classic way to synthesize furans. The reaction involves alkylation of 1,3-diketones with α-bromoketones followed by dehydration of an intermediate hydroxydihydrofuran. [9] The other traditional route involve the reaction of 1,4-diketones with phosphorus pentoxide (P 2 O 5) in the Paal–Knorr synthesis. [10]
Hydroboration–oxidation reaction is a two-step hydration reaction that converts an alkene into an alcohol. [1] The process results in the syn addition of a hydrogen and a hydroxyl group where the double bond had been.
The reaction conditions for the synthesis of each type of isobutylene product vary depending on the desired molecular weight and what type(s) of monomer(s) is used. The conditions most commonly used to form low molecular weight (5–10 x 10 4 Da) polyisobutylene are initiation with AlCl 3 , BF 3 , or TiCl 4 at a temperature range of −40 to 10 ...
This highly flammable, colorless, and moisture sensitive material is the simplest Grignard reagent and is commercially available, usually as a solution in tetrahydrofuran. Synthesis and reactions [ edit ]