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Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism.
Men and women exhibit different symptoms for hypergonadism. A few of the symptoms that men can experience are increased sex drive, early balding, excessive muscle mass, and acne. Women can have symptoms such as, increased growth of facial hair, deepened voice, coarse body hair, and an irregular menstrual cycle. [5]
A 2018 Cochrane review of studies on men over 60 with moderate to severe lower urinary tract symptoms analyzed the impacts of phosphodiesterase inhibitors (PDE) in comparison to other drugs. [90] These drugs may improve urinary symptoms slightly and reduce urinary bother but may also cause more side effects compared to placebo.
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American YouTube personality MrBeast is the most-subscribed channel on YouTube, with 343 million subscribers as of January 2025.. A subscriber to a channel on the American video-sharing platform YouTube is a user who has chosen to receive the channel's content by clicking on that channel's "Subscribe" button, and each user's subscription feed consists of videos published by channels to which ...
In 2014, a systematic review identified women as having slightly higher increased risks of developing hypertensive crises than do men. [ 5 ] With the usage of anti hypertensives, the rates of hypertensive emergencies has declined from 7% to 1% of patients with hypertensive urgency.
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Some lesser known uses are as a means of high-dose estrogen therapy in the treatment of breast cancer in both women and men and in the treatment of prostate cancer in men. [22] [23] It has been used at a dosage of 2.5 mg three times per day (7.5 mg/day total) for prostate cancer. [24] [25]