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Primidone, sold under various brand names (including Mysoline), is a barbiturate medication that is used to treat partial and generalized seizures [7] and essential tremors. [8] It is taken by mouth. [7] Its common side effects include sleepiness, poor coordination, nausea, and loss of appetite. [7] Severe side effects may include suicide and ...
Essential tremor (ET), also called benign tremor, familial tremor, and idiopathic tremor, is a medical condition characterized by involuntary rhythmic contractions and relaxations (oscillations or twitching movements) of certain muscle groups in one or more body parts of unknown cause. [6]
Essential tremor may be treated with beta blockers (such as propranolol and nadolol) or primidone, an anticonvulsant Cerebellar tremor symptoms may decrease with the application of alcohol (ethanol) or benzodiazepine medications, both of which carry some risk of dependence or addiction
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Expand : History section, essential tremor section, mechanism of action; Merge : Adverse effects sections; Verify : That it was Wyeth and that it was released no sooner than 1954. Other : Incorporate the following references somehow: Rosenbloom, David (February 1, 1983). "Drug treatment of epilepsy: a review". Canadian Medical Association Journal.
It has been demonstrated in essential tremor animal models that the food additive 1-octanol suppresses tremors induced by harmaline, and decreases the amplitude of essential tremor for about 90 minutes. [20] Two of the most valuable drug treatments for essential tremor are propranolol, a beta blocker, and primidone, an anticonvulsant ...
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