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At higher doses, niacin has been used to treat high cholesterol and triglyceride levels, since it can help lower LDL (“bad”) cholesterol and raise levels of HDL (“good”) cholesterol.
Although niacin and nicotinamide are identical in their vitamin activity, nicotinamide does not have the same pharmacological, lipid-modifying effects or side effects as niacin, i.e., when niacin takes on the -amide group, it does not reduce cholesterol nor cause flushing.
Pharmacologic (1- to 3-gram/day) niacin doses increase HDL levels by 10–30%, [61] making it the most powerful agent to increase HDL-cholesterol. [62] [63] A randomized clinical trial demonstrated that treatment with niacin can significantly reduce atherosclerosis progression and cardiovascular events. [64]
Level of the good cholesterol HDL is also increased. Fibrates may decrease LDL, though generally to a lesser degree than statins. Similar to statins, the risk of muscle damage exists. Nicotinic acid, like fibrates, is also well suited for lowering triglycerides by 20–50%. It may also lower LDL by 5–25% and increase HDL by 15–35%.
A six-ounce cut of top sirloin, for instance, contains calcium, selenium, niacin ... Saturated fat is problematic because it can raise LDL (bad) cholesterol levels ... "as they have a lower ...
The phenolic compounds and saponins in quinoa may help reduce the risk of cardiovascular disease and diabetes, and its soluble fiber helps decrease triglycerides and LDL levels in the body while ...
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