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White matter is the tissue through which messages pass between different areas of grey matter within the central nervous system. The white matter is white because of the fatty substance (myelin) that surrounds the nerve fibers (axons). This myelin is found in almost all long nerve fibers, and acts as an electrical insulation.
Myelin is formed by oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system.Therefore, the first stage of myelinogenesis is often defined as the differentiation of oligodendrocyte progenitor cells (OPCs) or Schwann cell progenitors into their mature counterparts, [4] followed by myelin formation around axons.
Myelin (/ ˈ m aɪ. ə l ɪ n / MY-ə-lin) is a lipid-rich material that surrounds nerve cell axons to insulate them and increase the rate at which electrical impulses (called action potentials) pass along the axon. [1] [2] The myelinated axon can be likened to an electrical wire (the axon) with insulating material (myelin) around it. However ...
Myelin basic protein (MBP) is a protein believed [weasel words] to be important in the process of myelination of nerves in the nervous system. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction . [ 5 ]
In white matter, OPCs are found along unmyelinated axons [10] as well as along myelinated axons, engulfing nodes of Ranvier. [11] [12] Recently, OPCs have been shown to reside in close contact with NG2-expressing pericytes in cerebral white matter, as well. [13]
Myelination is a process by which axons are covered with a protective substance called myelin that drastically increases the signaling efficiency of the neuron. [7] The arcuate fasciculus is heavily myelinated in healthy adult brains. The density of this myelination has been found to predict the accuracy and speed to which one can comprehend ...
White matter tracts within a human brain, as visualized by MRI tractography Rendering of a group connectome based on 20 subjects. Anatomical fibers that constitute the white matter architecture of the human brain are visualized color-coded by traversing direction (xyz-directions mapping to RGB colors respectively). Visualization of fibers was ...
The European Leukodystrophy Association also supports research into leukodystrophy. As of 2020, more than 387 research projects have been funded. Each year, ELA invites the international scientific community to submit research projects in the field of genetic leukodystrophies, the cerebral white matter in premature infants, and of myelin repair ...