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Salivary gland dysfunction affects the flow, amount, or quality of saliva produced. A reduced salivation is termed hyposalivation . Hyposalivation often results in a dry mouth condition called xerostomia , and this can cause tooth decay due to the loss of the protective properties of saliva.
Sjögren's syndrome: Chronic inflammation of the salivary glands may also be an autoimmune disease known as Sjögren's syndrome. The disease most commonly appears in people aged 40–60 years, but it may affect small children. In Sjögren syndrome, the prevalence of parotitis in women versus men is approximately 9:1.
Sialadenitis (sialoadenitis) is inflammation of salivary glands, usually the major ones, the most common being the parotid gland, followed by submandibular and sublingual glands. [1] It should not be confused with sialadenosis (sialosis) which is a non-inflammatory enlargement of the major salivary glands. [2]
Sjögren's disease (SjD) [8] [9] (previously known as Sjögren syndrome or Sjögren's syndrome (SjS, SS)) is a long-term autoimmune disease that primarily affects the body's exocrine glands, particularly the lacrimal and salivary glands.
A minor salivary gland biopsy, usually taken from the lip, [26] may be carried out if there is a suspicion of organic disease of the salivary glands. [1] Blood tests and urinalysis may be involved to exclude a number of possible causes. [1] To investigate xerophthalmia, the Schirmer test of lacrimal flow may be indicated. [1]
The two parotid glands are major salivary glands wrapped around the mandibular ramus in humans. [6] These are largest of the salivary glands, secreting saliva to facilitate mastication and swallowing, and amylase to begin the digestion of starches. [7] It is the serous type of gland which secretes alpha-amylase (also known as ptyalin). [8]
Gradual enlargement of the major salivary glands, particularly the parotid glands. [3] This swelling may be on one side or both sides, may cause disfigurement and may be painful. [2] Xerostomia (dry mouth) with no other cause such as a side effect of medications. [2] HIV-SGD may be the presenting sign of HIV infection. [3]
Chronic sclerosing sialadenitis is a chronic (long-lasting) inflammatory condition affecting the salivary gland.Relatively rare in occurrence, this condition is benign, but presents as hard, indurated and enlarged masses that are clinically indistinguishable from salivary gland neoplasms or tumors.