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Evolution of fish to tetrapods. The basic body plan has been phylogenetically constrained. Most terrestrial vertebrates have a body plan that consist of four limbs. The phylogenetic inertia hypothesis suggests that this body plan is observed, not because it happens to be optimal, but because tetrapods are derived from a clade of fishes (Sarcopterygii) which also have four limbs.
Biological constraints are factors which make populations resistant to evolutionary change. One proposed definition of constraint is "A property of a trait that, although possibly adaptive in the environment in which it originally evolved, acts to place limits on the production of new phenotypic variants."
These transcription factors contain the homeobox protein-binding DNA motif, also found in other toolkit genes, and create the basic pattern of the body along its front-to-back axis. [1] Hox genes determine where repeating parts, such as the many vertebrae of snakes, will grow in a developing embryo or larva. [9]
A phylogenetic analysis typically consists of five major steps. The first stage comprises sequence acquisition. The following step consists of performing a multiple sequence alignment, which is the fundamental basis of constructing a phylogenetic tree. The third stage includes different models of DNA and amino acid substitution.
The evolution of tetrapods began about 400 million years ago in the Devonian Period with the earliest tetrapods evolved from lobe-finned fishes. [1] Tetrapods (under the apomorphy-based definition used on this page) are categorized as animals in the biological superclass Tetrapoda, which includes all living and extinct amphibians, reptiles, birds, and mammals.
Comparison to larval morphology has indicated that the specimens have a close relationship to either genus Chaetopterus or genus Mesochaetopterus, and a phylogenetic tree constructed from mitochondrial and ribosomal DNA sequences from twelve different Chaetopteridae worms found them to be most closely related to other worms of the genus ...
Phylogenetic comparative methods (PCMs) use information on the historical relationships of lineages (phylogenies) to test evolutionary hypotheses. The comparative method has a long history in evolutionary biology; indeed, Charles Darwin used differences and similarities between species as a major source of evidence in The Origin of Species .
Phylogenetic bracketing is a method of inference used in biological sciences. It is used to infer the likelihood of unknown traits in organisms based on their position in a phylogenetic tree. One of the main applications of phylogenetic bracketing is on extinct organisms, known only from fossils, going back to the last universal common ancestor ...