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  2. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes, or symptomatic heart failure.

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]

  4. Andexanet alfa - Wikipedia

    en.wikipedia.org/wiki/Andexanet_alfa

    Andexanet alfa, sold under the brand name Andexxa among others, is an antidote for the medications rivaroxaban and apixaban, when reversal of anticoagulation is needed due to uncontrolled bleeding. [8] It has not been found to be useful for other factor Xa inhibitors. [9] It is given by injection into a vein. [9]

  5. FDA Accepts Eliquis® (apixaban) Supplemental New Drug ... - AOL

    www.aol.com/2013/07/11/fda-accepts-eliquis...

    FDA Accepts Eliquis ® (apixaban) Supplemental New Drug Application for Review for Prophylaxis of Deep Vein Thrombosis Following Hip Or Knee Replacement Surgery PRINCETON, N.J. & NEW YORK ...

  6. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The p-methoxy group of apixaban connects to S1 pocket of FXa but does not appear to have any interaction with any residues in this region of FXa. The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due ...

  7. Study Finds Changes in Cholesterol May Indicate Higher ...

    www.aol.com/study-finds-changes-cholesterol-may...

    It determined that low-dose aspirin was not effective in reducing heart disease risk in Australian and American adults. Worth noting: White adults made up 96% of the study, so the findings may not ...

  8. Antiplatelet drug - Wikipedia

    en.wikipedia.org/wiki/Antiplatelet_drug

    Antiplatelet medications are one of the primary recommendations for treatment of both stable [4] and unstable [5] ischemic heart disease.Most commonly, aspirin is used as a single medication in cases of uncomplicated stable angina, and in some cases of unstable angina.

  9. From frozen waffles to onions: How recent recalls highlight ...

    www.aol.com/frozen-waffles-onions-recent-recalls...

    From E. coli traced to slivered onions on McDonald's Quarter Pounders to mass recalls of frozen waffles due to listeria risk, foodborne illness seems ever-present in the headlines.

  1. Related searches apixaban usual dose recommendations for children 40

    apixaban usual dose recommendations for children 40 lbs