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The metaphysis (pl.: metaphyses) is the neck portion of a long bone between the epiphysis and the diaphysis. [1] It contains the growth plate , the part of the bone that grows during childhood, and as it grows it ossifies near the diaphysis and the epiphyses.
An epiphyseal line is an epiphyseal plate that has become ossified. [1] The process of it forming from an epiphyseal plate is named epiphyseal closure . [ 2 ] In adult humans, it marks the point of fusion between the epiphysis and the metaphysis .
On X-ray, giant-cell tumors (GCTs) are lytic/lucent lesions that have an epiphyseal location and grow to the articular surface of the involved bone. [8] Radiologically the tumors may show characteristic 'soap bubble' appearance. [9] They are distinguishable from other bony tumors in that GCTs usually have a nonsclerotic and sharply defined border.
3D medical illustration depicting the TNM stages in breast cancer. Cancer staging can be divided into a clinical stage and a pathologic stage. In the TNM (Tumor, Node, Metastasis) system, clinical stage and pathologic stage are denoted by a small "c" or "p" before the stage (e.g., cT3N1M0 or pT2N0).
Epiphyseal growth plate: This transverse layer lies between the epiphysis and diaphysis. It’s composed of highly active chondrocytes and responsible for longitudinal bone growth. Consequently, the bone elongates at this growth plate until closure occurs at skeletal maturity.
[3] [4] Between the epiphysis and diaphysis (the long midsection of the long bone) lies the metaphysis, including the epiphyseal plate (growth plate). During formation of the secondary ossification center, vascular canals (epiphysial canals) stemming from the perichondrium invade the epiphysis, supplying nutrients to the developing secondary ...
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At the end of the formation of the secondary ossification center, the only two areas where the cartilage remains is at the articular cartilage covering the epiphysis and at the epiphyseal plate between the epiphysis and diaphysis. [3] A schematic for long bone endochondral ossification: [4]